Wednesday, November 6, 2013

Pharm Notes

Ch 50- Acid Controlling drugs Ant acrids- Neutralize stomach panellings -Aluminum Salts- constipating effects, frequently apply w/ magnesium to counteract, often used with patients with nephritic distemper (easily excreted) -Magnesium salts- commonly develop diarrhea -Calcium salts- whitethorn execute constipation and kidney stones, desire duration of astringent action, -Sodium Bicarbonate- quick onset, presently duration. May cause metabolic alkalosis, sodium content whitethorn cause problems w/ patients w/ HF hypertension bring out meds 1-2 hours after antacid Antiflatulents- drugs: Simethicone, Activated Charcoal H2 Antagonists- bowdlerize acid secretion Cimetidine (Tagament)- Binds with P-450, resulting in increased drug levels ranitidine (Zantac) Smoking decreases effectiveness of h2 blockers Proton Pump Inhibitors- achlorhydriaALL stomachal acid secretion is temporarily blocked Used for GERD maintenance therapy, blistering esophagitis, sh ort-term treatment of active duodenal and benign gastric ulcers, Zollinger-Ellison syndrome, manipulation of H. pyloriinduced ulcers. Proton pump inhibitors often work stovepipe when taken 30 to 60 minutes to begin with meals omeprazole (Prilosec) Pantoprazole (Protonix)- specifically indicated treatment of h pylori, may increase release with warfarin.
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other drugs: Sucralfate (Carafate)- forming a protective barrier oer ulcers, demo other drugs at least 2 hours before sucralfate, may be used in chronic renal bereavement to reduce phosphate levels Misoprostol (Cytotec)- Used for prevention of NS AID-induced gastric ulcers, value gastric m! ucosa from injury by enhancing topical anaesthetic end product of mucus Ch 51- Bowel Disorder Drugs Antidiarrheals- -Adsorbents: show up walls of GI tract, bind to responsible bacteria or toxin indeed eliminated through stool. Examples: bismuth subsalicylate (Pepto-Bismol). change magnitude bleeding time. bad Gums, Tinnitis, hearing loss, dark stools. Decreased engrossment of digoxin, clindamycin, quinidine, hypoglycemic drugs. NO PEPTO BISMOL TO...If you want to get a encompassing essay, order it on our website: OrderCustomPaper.com

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